The shape of the pharmacokinetic curve is a function of drug dissolution, rate and extent of absorption across the gastro-intestinal...

In critical care medicine, the goal is to deliver therapeutic drug concentrations rapidly in blood and then maintain therapeutic concentrations...

Ramesh Jayaraman DoseQuartics Consulting Steady state concentrations and accumulation Selection of dosing regimen is as important as dose for designing...

Ramesh Jayaraman DoseQuartics Consulting The Exposure (AUC) of a therapeutic when administered as infusions and bolus When a dose of...

There is a causal relationship between dose, dosage regimen, exposure of drug and its therapeutic benefit and adverse effects (1). To...