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PHARMACOKINETICS (PK)

  • Estimation of Non-compartmental PK parameters in preclinical species and humans
  • Estimation of Compartmental PK parameters in preclinical species and humans
  • Dose Proportionality Analysis
  • Modelling of PK data in preclinical species and humans
  • Modelling and simulation of pharmacokinetics
  • Prediction of Human PK parameters by Allometric scaling
  • Design of PK studies, analysis and interpretation of PK data

PHARMACODYNAMICS (PD)

  • Estimation of in vitro Pharmacodynamic parameters
  • Estimation of in vivo Pharmacodynamic parameters
  • Modelling of Pharmacodynamic data in preclinical species
  • Modelling and Simulation of Pharmacodynamics
  • Design of Pharmacology studies, Analysis and Interpretation of Pharmacodynamic data

PHARMACOKINETICS / PHARMACODYNAMICS (PK/PD)

  • Design of PK/PD studies, analysis and interpretation of PK/PD data
  • Dose Exposure Response analysis
  • Modelling and Simulation of PK/PD data

DRUG DISCOVERY AND DEVELOPMENT

  • Preparing project plans, data analysis, interpretation, decision making for Lead Identification, Lead Optimization, Preclinical Development and Clinical Development programs

ADME STUDIES

  • Design of in vitro ADME studies, Analysis and Interpretation of data
  • Design of in vivo ADME studies, analysis and interpretation of data