Volume of distribution (V) and Clearance (CL) are fundamental pharmacokinetic (PK) parameters that determine the PK properties of a molecule.…

Chemotherapy with targeted drugs in cancer is based on the presence of the abnormally expressed drug target (driver mutations that…

The primary clinical endpoint used for measuring the efficacy of an anti-cancer therapy is Progression Free Survival (PFS) or Overall…

For any drug discovery company, a major milestone is the administration of the clinical drug candidate for the first time…

Ramesh Jayaraman Director DoseQuantics Consulting INTRODUCTION The pharmacokinetics (time course of concentration in the body) of a drug when combined…