Ramesh Jayaraman, DoseQuantics Consulting, September 12th 2025 The true worth of an anti-cancer drug is measured not just by its ability...

Ramesh Jayaraman, DoseQuantics Consulting Pvt Ltd. 7th September, 2025 Recently, two letters to the editors appeared in the journal Antimicrobial Agents...

Drugs are combined to achieve a specific pharmacodynamic objective a) increase efficacy (eg cancer treatment) b)  reduce development of resistance...

Clearance (CL) relates the rate of elimination of a molecule with its concentration in vivo. Many small molecules are cleared...

The discharge of antibiotics into the environment such as excretion of intact antibiotic drugs from humans (during treatment of infections)...

There are many drugs that are extensively metabolized by the liver by drug metabolizing enzymes (DME). In many cases a...

Dose fractionation (DF) is an experimental method used to identify the pharmacokinetic/pharmacodynamic (PK/PD) index of an anti-bacterial molecule. Two non-compartmental...